Bio signals include electrocardiogram (ECG), electroencephalogram (EEG), electromyography (EMG), respiratory signals, body and gaze movements, and daily behavioral patterns. These signals constantly carry an important information about our mental and physical health and are used to assess mental workload states, emotional states and health states. The research aims of our laboratory are to investigate the characteristics and the mechanisms of bio signals through the analysis of the signals and to develop novel methods for applying life sciences, medicine, education, artistic culture and sports.